Ostenil Injections

What is Ostenil?

Ostenil is a treatment for the symptoms of osteoarthritis. It can be injected into any of the synovial joints and I have been getting some very good results when used in the knee, the shoulder and the thumb joints.

Ostenil is a solution containing Hyaluronic acid and Mannitol (a simple sugar derivative).

The hyaluronic acid in Ostenil is very pure and is manufactured using a process called fermentation. It contains no animal proteins, which means it is very unlikely to cause an allergic reaction. Ostenil has been extensively tested, and has not been found to cause any serious side effects.

The addition of Mannitol to Hyaluronic Acid allows the Ostenil to work for longer and more efficiently in the joint, enabling effective symptom reduction with a single injection.

It is injected into the space in the joint that contains synovial fluid and works by restoring the normal balance between the breakdown and production of hyaluronic acid. This effect of Ostenil means that it can decrease pain and stiffness and improve the other symptoms of osteoarthritis.

Ostenil is marketed in 2 sizes Ostenil Plus (40mg in 2ml) and Ostenil Mini (10mg in 1ml). The dose administered is chosen depending on the size of the joint.

Ostenil also comes marketed as Ostenil Tendon. It is essentially the same product and as the name suggests is suitable for use in tendon problems such as De Quervains Tenosynovitis.

What is Ostenil Used?

Most joints in the human body fall under the category of “synovial joints”.

A synovial joint is one in which the ends of the bones are enclosed in a capsule containing a thick, slippery liquid called synovial fluid. The capsule is made of strong, fibrous tissue and is lined with a membrane called the synovial membrane. The bone ends are covered in a smooth layer of a tough, rubbery substance known as cartilage.

The synovial fluid in the joint capsule has four important functions:-
It keeps the bones slightly apart, protecting their cartilage coverings from wear and tear.
It absorbs shocks, again protecting the cartilage.
It lubricates the joint, helping it to work freely and easily .
It acts as a filter, letting nutrients reach the cartilage, but blocking the passage of harmful cells and substances.

The most important component of synovial fluid is a substance called hyaluronic acid. It is this substance that lets synovial fluid perform its four different functions all at the same time. Most of the joints in your body are synovial joints. Good examples, besides the knee, include the hip and the shoulder.

What happens in Osteoarthrosis?

The hyaluronic acid in the synovial fluid does not stay there for a whole lifetime, but is continuously broken down and replaced. Normally, there is an exact balance between the breakdown of old hyaluronic acid and the production of new hyaluronic acid. In osteoarthritis, however, this balance is disturbed and breakdown happens faster than production. As a result, the synovial fluid becomes more watery and stops working properly.

Due to the change in the synovial fluid – and for other, more complex reasons – the cartilage in the joint gradually wears away. In some places, in fact, the cartilage may eventually disappear altogether. The thinning of the synovial fluid and wearing away of the articular cartilage leads to the symptoms of osteoarthritis, which include pain, stiffness and swelling.

Osteoarthritis develops as people get older and is present in almost everybody over the age of 60 (although not everyone in this age group has bad symptoms). Osteoarthritis of the knee or hip may also occur in younger people, usually (but not always) because these joints have been overloaded.

Possible causes of overloading include sports, jobs involving a lot of lifting and carrying, too much bodyweight and abnormal joint development.

Ostenil has been extensively tested, and has not been found to cause any serious side effects.

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